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Pyrrolizidine poisoning is common in Africa and Jamaica, two areas of the world where herbal teas containing this substance are consumed as folk remedies for a number of ailments

Mechanistically, Epitalons effect appears to involve a direct interaction with promoter regions of the telomerase gene, where it binds specific DNA sequences (such as ATTTC motifs), potentially modulating transcriptional activity

As an essential vitamin responsible for energy production, nervous system function, and metabolic support, B12 plays a critical role in how the body and mind perform each day

The initial search yielded 12 articles, which were screened for duplicates and relevance based on titles and abstracts

Iannello RC